Content and Language Integrated Learning (CLIL) is an approach for learning content through an additional language (foreign or second), thus teaching both the subject and the language simultaneously. This approach to teaching and learning has never featured as strongly on university curricula as it does now. Besides, the great revolution of Information and Communication Technology (ICT) has had a tremendous impact on education. For the development of foreign language communication skills in particular, ICT is an ideal platform for developing interactive strategies and methodologies that promote independent learning, peer interaction, and language use for real communicative purposes. In a world where broadband connections and mobile-data enabled smartphones are widespread, and where students are digital natives, there is great potential for combining CLIL with ICT. If we add to this the opportunities that international university partnerships and networks offer for student interaction across borders, we have all the necessary ingredients for a successful course.